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Nature Communications|March 2, 2021
Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)Kengo Watanabe, Kazuhiro Morishita, Xiangyu Zhou, et al.Bioorganic & Medicinal Chemistry Letters|April 6, 2017
Synthesis and SAR studies of 3,6-disubstituted indazole derivatives as potent hepcidin production inhibitorsTakeshi Fukuda, Kenjiro Ueda, Takashi Ishiyama, et al.Bioorganic & Medicinal Chemistry Letters|July 15, 2017
Discovery of DS79182026: A potent orally active hepcidin production inhibitorTakeshi Fukuda, Riki Goto, Toshihiro Kiho, et al.Clinical Journal of Gastroenterology|August 1, 2025
Giant hepatic hemangioma in a Japanese adult patient reduced by sirolimus therapyMio Tsuruoka, Masashi Ninomiya, Jun Inoue, et al.Bioorganic & Medicinal Chemistry Letters|October 29, 2017
Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivativesTakeshi Fukuda, Riki Goto, Toshihiro Kiho, et al.Hepatology Research : the Official Journal of the Japan Society of Hepatology|March 18, 2026
Clinical Significance of Anti-Atezolizumab Antibodies in Patients With Unresectable Hepatocellular Carcinoma Treated With Atezolizumab Plus BevacizumabKeishi Ouchi, Jun Inoue, Masashi Ninomiya, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 31, 2020
Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic ModelsMakiko Yamada, Shin-Ichi Inoue, Daisuke Sugiyama, et al.Bioorganic & Medicinal Chemistry Letters|September 16, 2018
Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivativesTakeshi Fukuda, Takashi Ishiyama, Takahiro Katagiri, et al.Journal of Medicinal Chemistry|October 1, 2004
Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding elementNoriyasu Haginoya, Syozo Kobayashi, Satoshi Komoriya, et al.The Journal of Biological Chemistry|March 8, 2020
The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1Sho Sugawara, Yusuke Kanamaru, Shiori Sekine, et al.Pageof 6