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Journal of Medicinal Chemistry|January 8, 2008
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory painMichael E Kort, Irene Drizin, Robert J Gregg, et al.Journal of Medicinal Chemistry|December 8, 2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunctionMeena V Patel, Teodozyj Kolasa, Kathleen Mortell, et al.Journal of Medicinal Chemistry|January 24, 2012
Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1Vince S C Yeh, David W A Beno, Sevan Brodjian, et al.Molecular Cancer Therapeutics|March 31, 2021
Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy VolunteersAhmed Hamed Salem, Zhi-Fu Tao, Orlando F Bueno, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 3, 2007
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor modelsCherrie K Donawho, Yan Luo, Yanping Luo, et al.CNS Neuroscience & Therapeutics|May 17, 2008
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesKarin R Tietje, David J Anderson, R Scott Bitner, et al.Nature Medicine|January 8, 2013
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing plateletsAndrew J Souers, Joel D Leverson, Erwin R Boghaert, et al.Antimicrobial Agents and Chemotherapy|June 27, 2018
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of MalariaChristel Brunschwig, Nina Lawrence, Dale Taylor, et al.Science Translational Medicine|April 28, 2017
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinaseTanya Paquet, Claire Le Manach, Diego González Cabrera, et al.Pageof 11