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Nucleic Acids Research|March 14, 2022
Predicting exon criticality from protein sequenceJigar Desai, Christopher Francis, Kenneth Longo, et al.Translational Vision Science & Technology|January 29, 2021
Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple SpeciesMichael Byrne, Vinod Vathipadiekal, Luciano Apponi, et al.Nature Communications|February 9, 2021
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical modelsYuanjing Liu, Jean-Cosme Dodart, Helene Tran, et al.Nucleic Acids Research|August 16, 2024
Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editingGenliang Lu, Chikdu Shivalila, Prashant Monian, et al.Nucleic Acids Research|February 2, 2022
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNSPachamuthu Kandasamy, Yuanjing Liu, Vincent Aduda, et al.Nucleic Acids Research|January 21, 2022
Control of backbone chemistry and chirality boost oligonucleotide splice switching activityPachamuthu Kandasamy, Graham McClorey, Mamoru Shimizu, et al.Pageof 1