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Kentaro Futatsugi

Showing results (11-20 of 24) with videos related to

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Bioorganic & Medicinal Chemistry Letters|January 23, 2013
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial librariesAllyn T Londregan, David W Piotrowski, Kentaro Futatsugi, et al.
Journal of Medicinal Chemistry|January 5, 2018
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid AntagonistsDavid W Piotrowski, Kentaro Futatsugi, Agustin Casimiro-Garcia, et al.
Bioorganic & Medicinal Chemistry Letters|February 12, 2011
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptorVincent Mascitti, Benjamin D Stevens, Chulho Choi, et al.
ACS Medicinal Chemistry Letters|October 18, 2023
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-LifeKevin J Filipski, David J Edmonds, Michelle R Garnsey, et al.
Journal of Medicinal Chemistry|March 3, 2011
Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist responseKim F McClure, Etzer Darout, Cristiano R W Guimarães, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptorKentaro Futatsugi, Vincent Mascitti, Cristiano R W Guimarães, et al.
Journal of Medicinal Chemistry|January 7, 2016
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) FamilyKim Huard, James R Gosset, Justin I Montgomery, et al.
Scientific Reports|December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)Kim Huard, Janice Brown, Jessica C Jones, et al.
Nature Communications|May 16, 2025
Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca<sup>2+</sup> dependent allosteric binding siteLeslie A Dakin, Li Xing, Justin Hall, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 AgonistsDavid W Piotrowski, Kentaro Futatsugi, Joseph S Warmus, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Bioorganic & Medicinal Chemistry Letters|January 23, 2013
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial librariesAllyn T Londregan, David W Piotrowski, Kentaro Futatsugi, et al.
Journal of Medicinal Chemistry|January 5, 2018
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid AntagonistsDavid W Piotrowski, Kentaro Futatsugi, Agustin Casimiro-Garcia, et al.
Bioorganic & Medicinal Chemistry Letters|February 12, 2011
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptorVincent Mascitti, Benjamin D Stevens, Chulho Choi, et al.
ACS Medicinal Chemistry Letters|October 18, 2023
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-LifeKevin J Filipski, David J Edmonds, Michelle R Garnsey, et al.
Journal of Medicinal Chemistry|March 3, 2011
Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist responseKim F McClure, Etzer Darout, Cristiano R W Guimarães, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptorKentaro Futatsugi, Vincent Mascitti, Cristiano R W Guimarães, et al.
Journal of Medicinal Chemistry|January 7, 2016
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) FamilyKim Huard, James R Gosset, Justin I Montgomery, et al.
Scientific Reports|December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)Kim Huard, Janice Brown, Jessica C Jones, et al.
Nature Communications|May 16, 2025
Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca<sup>2+</sup> dependent allosteric binding siteLeslie A Dakin, Li Xing, Justin Hall, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 AgonistsDavid W Piotrowski, Kentaro Futatsugi, Joseph S Warmus, et al.
Pageof 3