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Scientific Reports|January 14, 2022
Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, et al.Scientific Reports|March 26, 2022
Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitroThoai Quoc Kieu, Kento Tazawa, Nobuyuki Kawashima, et al.Biochemical and Biophysical Research Communications|November 27, 2019
HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cellsMayuko Fujii, Nobuyuki Kawashima, Kento Tazawa, et al.International Journal of Molecular Sciences|September 14, 2024
MicroRNA-27a-5p Downregulates Expression of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Human Dental Pulp Cells via the NF-κB Signaling PathwayShihan Wang, Nobuyuki Kawashima, Peifeng Han, et al.Journal of Translational Medicine|February 16, 2025
MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivoZiniu Yu, Nobuyuki Kawashima, Keisuke Sunada-Nara, et al.Journal of Oral Biosciences|July 4, 2026
Metformin suppresses periapical bone resorption in a mouse model of apical periodontitis in vivo and inhibits RANKL-induced osteoclastogenesis in vitroFaisal Alghamdi, Chunmei Ren, Kento Tazawa, et al.Frontiers in Immunology|August 18, 2025
Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7 through the AMPK-mTOR-NF-κB pathwayChunmei Ren, Kento Tazawa, Nobuyuki Kawashima, et al.Pageof 2