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International Journal of Molecular Sciences|December 24, 2021
A Systematic Approach to Assess the Activity and Classification of PCSK9 VariantsKepa B Uribe, Kevin Chemello, Asier Larrea-Sebal, et al.
Biomedicines|September 26, 2020
Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid CompositionShifa Jebari-Benslaiman, Kepa B Uribe, Asier Benito-Vicente, et al.
Small (Weinheim an Der Bergstrasse, Germany)|February 14, 2022
Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis ModelShifa Jebari-Benslaiman, Kepa B Uribe, Asier Benito-Vicente, et al.
Scientific Reports|February 5, 2020
Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLRUnai Galicia-Garcia, Asier Benito-Vicente, Kepa B Uribe, et al.
Frontiers in Oncology|September 5, 2022
Decellularization of xenografted tumors provides cell-specific in vitro 3D environmentGaia Iazzolino, Unai Mendibil, Blanca Arnaiz, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|October 4, 2019
Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR ActivityPoulabi Banerjee, Kuo-Chen Chan, Michel Tarabocchia, et al.
Atherosclerosis|June 24, 2017
Analysis of LDLR variants from homozygous FH patients carrying multiple mutations in the LDLR geneLong Jiang, Asier Benito-Vicente, Ling Tang, et al.
JACC. Basic to Translational Science|December 6, 2021
MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense VariantsAsier Larrea-Sebal, Asier Benito-Vicente, José A Fernandez-Higuero, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|May 5, 2022
Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant HypercholesterolemiaAsier Benito-Vicente, Kepa B Uribe, Asier Larrea-Sebal, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|January 23, 2024
OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic ResiduesAsier Larrea-Sebal, Iñaki Sasiain, Shifa Jebari-Benslaiman, et al.
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