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Nucleic Acids Research|August 31, 2023
Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcriptionJingke Xie, Zhenpeng Zhuang, Shixue Gou, et al.
Signal Transduction and Targeted Therapy|July 18, 2024
In vivo evaluation of guide-free Cas9-induced safety risks in a pig modelWeikai Ge, Shixue Gou, Xiaozhu Zhao, et al.
Stem Cell Research|October 17, 2017
Generation of three miR-122 knockout lines from a human embryonic stem cell lineYanli Liu, Feima Wu, Yuanqi Zhuang, et al.
Molecular Therapy. Nucleic Acids|October 9, 2023
Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryosWeikai Ge, Xiaozhu Zhao, Shixue Gou, et al.
Human Molecular Genetics|December 25, 2016
Generation of Hoxc13 knockout pigs recapitulates human ectodermal dysplasia-9Kai Han, Liuping Liang, Li Li, et al.
Nature Communications|January 17, 2026
Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutionsShuangshuang Mu, Qianru Li, Menglong Chen, et al.
Nucleic Acids Research|May 11, 2022
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patternsYanhui Liang, Jingke Xie, Quanjun Zhang, et al.
Genome Biology|January 17, 2023
Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activationQin Jin, Xiaoyi Liu, Zhenpeng Zhuang, et al.
BMC Biology|September 24, 2020
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systemsJingke Xie, Xingyun Huang, Xia Wang, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|November 22, 2020
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type INan Li, Shixue Gou, Jiaowei Wang, et al.
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