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ACS Chemical Biology|April 27, 2019
The Lasso Peptide Siamycin-I Targets Lipid II at the Gram-Positive Cell SurfaceStephanie Tan, Kevin C Ludwig, Anna Müller, et al.International Journal of Molecular Sciences|October 23, 2021
Host Defense Peptides: Dual Antimicrobial and Immunomodulatory ActionMatthew Drayton, Julia P Deisinger, Kevin C Ludwig, et al.Nature Communications|March 21, 2020
Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipidsFabian Grein, Anna Müller, Katharina M Scherer, et al.ACS Infectious Diseases|June 6, 2024
Synthesis of Bisindole Alkaloids and Their Mode of Action against Methicillin-Resistant Staphylococcus AureusEmmanuel T Adeniyi, Marco Kruppa, Stefania De Benedetti, et al.Antibiotics (Basel, Switzerland)|April 23, 2022
Impacts of NaHCO3 on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO3-Responsive versus NaHCO3-Non-Responsive PhenotypesSelvi C Ersoy, Liana C Chan, Michael R Yeaman, et al.Proceedings of the National Academy of Sciences of the United States of America|November 17, 2021
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediatesElisabeth Reithuber, Torbjörn Wixe, Kevin C Ludwig, et al.Angewandte Chemie (International Ed. in English)|March 26, 2021
Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic HypeptinDaniel A Wirtz, Kevin C Ludwig, Melina Arts, et al.Journal of the American Chemical Society|August 28, 2024
The Dual Mode of Antibacterial Action of the Synthetic Small Molecule DCAP Involves Lipid II BindingKevin C Ludwig, Jan-Samuel Puls, Cruz L Matos de Opitz, et al.Biorxiv : the Preprint Server for Biology|June 9, 2023
A new antibiotic from an uncultured bacterium binds to an immutable targetRhythm Shukla, Aaron J Peoples, Kevin C Ludwig, et al.Cell|August 23, 2023
An antibiotic from an uncultured bacterium binds to an immutable targetRhythm Shukla, Aaron J Peoples, Kevin C Ludwig, et al.Pageof 1