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Kevin Embrey

Showing results (1-10 of 9) with videos related to

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ADMET & DMPK|April 1, 2022
Biophysical methods in early drug discoveryGeoffrey Holdgate, Kevin Embrey, Alexander Milbradt, et al.
Plos One|March 22, 2016
MTH1 Substrate Recognition--An Example of Specific PromiscuityJ Willem M Nissink, Michal Bista, Jason Breed, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, et al.
ACS Medicinal Chemistry Letters|January 25, 2021
Structural Basis for Targeting the Folded P-Loop Conformation of c-METGavin W Collie, Iacovos N Michaelides, Kevin Embrey, et al.
Nature Communications|June 15, 2019
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobeNicolas Bery, Sandrine Legg, Judit Debreczeni, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2005
Structure-based design of protein tyrosine phosphatase-1B inhibitorsEmma Black, Jason Breed, Alexander L Breeze, et al.
Journal of Medicinal Chemistry|February 20, 2015
Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activationJon J G Winter, Malcolm Anderson, Kevin Blades, et al.
Antimicrobial Agents and Chemotherapy|December 21, 2011
Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agentsAnn E Eakin, Oluyinka Green, Neil Hales, et al.
Journal of Medicinal Chemistry|September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPsJeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Pageof 1

Showing results (1-10 of 9) with videos related to

Sort By:
Pageof 1
ADMET & DMPK|April 1, 2022
Biophysical methods in early drug discoveryGeoffrey Holdgate, Kevin Embrey, Alexander Milbradt, et al.
Plos One|March 22, 2016
MTH1 Substrate Recognition--An Example of Specific PromiscuityJ Willem M Nissink, Michal Bista, Jason Breed, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, et al.
ACS Medicinal Chemistry Letters|January 25, 2021
Structural Basis for Targeting the Folded P-Loop Conformation of c-METGavin W Collie, Iacovos N Michaelides, Kevin Embrey, et al.
Nature Communications|June 15, 2019
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobeNicolas Bery, Sandrine Legg, Judit Debreczeni, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2005
Structure-based design of protein tyrosine phosphatase-1B inhibitorsEmma Black, Jason Breed, Alexander L Breeze, et al.
Journal of Medicinal Chemistry|February 20, 2015
Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activationJon J G Winter, Malcolm Anderson, Kevin Blades, et al.
Antimicrobial Agents and Chemotherapy|December 21, 2011
Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agentsAnn E Eakin, Oluyinka Green, Neil Hales, et al.
Journal of Medicinal Chemistry|September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPsJeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Pageof 1