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Nature|August 6, 2010
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locusKiran Musunuru, Alanna Strong, Maria Frank-Kamenetsky, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 22, 2021
The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to HumanRobin McDougall, Diane Ramsden, Sagar Agarwal, et al.Proceedings of the National Academy of Sciences of the United States of America|August 13, 2008
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primatesMaria Frank-Kamenetsky, Aldo Grefhorst, Norma N Anderson, et al.Nucleic Acids Research|March 2, 2019
Safety evaluation of 2'-deoxy-2'-fluoro nucleotides in GalNAc-siRNA conjugatesMaja M Janas, Ivan Zlatev, Ju Liu, et al.British Journal of Cancer|November 19, 2022
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomesHeather J Bax, Jitesh Chauhan, Chara Stavraka, et al.Nature Nanotechnology|May 13, 2014
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weightJames E Dahlman, Carmen Barnes, Omar Khan, et al.Nucleic Acids Research|December 10, 2024
High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combinationYesseinia I Anglero-Rodriguez, Florian A Lempp, Megha Subramanian, et al.Nature Biotechnology|June 2, 2022
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugatesKirk M Brown, Jayaprakash K Nair, Maja M Janas, et al.Pageof 10