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Nucleic Acids Research|April 30, 2020
Generation and validation of structurally defined antibody-siRNA conjugatesAlex R Nanna, Alexander V Kel'in, Christopher Theile, et al.
Journal of the American Society of Nephrology : JASN|July 20, 2016
An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary HyperoxaluriaAbigail Liebow, Xingsheng Li, Timothy Racie, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 19, 2010
Crystal structure of Spot 14, a modulator of fatty acid synthesisChristopher L Colbert, Chai-Wan Kim, Young-Ah Moon, et al.
Molecular Therapy. Methods & Clinical Development|June 14, 2019
Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia GravisLinda L Kusner, Kristina Yucius, Manjistha Sengupta, et al.
Cell Metabolism|October 9, 2012
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in miceJae-Seon So, Kyu Yeon Hur, Margarite Tarrio, et al.
Toxicology and Applied Pharmacology|January 26, 2020
Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assayPierre Morissette, Sebastian Polak, Anne Chain, et al.
Mabs|May 16, 2025
Hybrid IgE-IgG1 antibodies (IgEG): a new antibody class that combines IgE and IgG functionalityMelanie Grandits, Lais C G F Palhares, Olivia Macleod, et al.
Neurology|October 22, 2020
Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated AmyloidosisSimina Ticau, Gautham V Sridharan, Shira Tsour, et al.
The New England Journal of Medicine|December 14, 2016
A Highly Durable RNAi Therapeutic Inhibitor of PCSK9Kevin Fitzgerald, Suellen White, Anna Borodovsky, et al.
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