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Kevin J Filipski

Showing results (31-40 of 34) with videos related to

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Nature Communications|August 9, 2023
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levelsRachel J Roth Flach, Eliza Bollinger, Allan R Reyes, et al.
Journal of Medicinal Chemistry|November 19, 2024
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948Kevin J Filipski, Luis A Martinez-Alsina, Matthew R Reese, et al.
Journal of Medicinal Chemistry|February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry|December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitusJeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
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Showing results (31-40 of 34) with videos related to

Sort By:
Pageof 4
You have reached the last page of results.This site can display upto 34 results.
Nature Communications|August 9, 2023
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levelsRachel J Roth Flach, Eliza Bollinger, Allan R Reyes, et al.
Journal of Medicinal Chemistry|November 19, 2024
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948Kevin J Filipski, Luis A Martinez-Alsina, Matthew R Reese, et al.
Journal of Medicinal Chemistry|February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry|December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitusJeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
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