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Cancer Medicine|November 14, 2023
A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemiaAref Al-Kali, Ibrahim Aldoss, Pamela J Atherton, et al.
The Journal of Biological Chemistry|November 6, 2009
Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergyXue Wei Meng, Michael P Heldebrant, Karen S Flatten, et al.
Nucleic Acids Research|February 16, 2017
Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesisReeja S Maskey, Karen S Flatten, Cynthia J Sieben, et al.
Haematologica|September 3, 2013
Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cellsHusheng Ding, Jennifer S McDonald, Seongseok Yun, et al.
Haematologica|April 4, 2024
A phase I study of pevonedistat, azacitidine, and venetoclax in patients with relapsed/refractory acute myeloid leukemiaGuru Subramanian Guru Murthy, Antoine N Saliba, Aniko Szabo, et al.
Blood|February 27, 2016
4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cellsSeongseok Yun, Nicole D Vincelette, Katherine L B Knorr, et al.
Nature Structural & Molecular Biology|January 8, 2026
Redox-driven ADAR1 activation promotes Okazaki fragment maturation and DNA replication integrityBin Chen, Guangchao Sun, Jake A Kloeber, et al.
Blood|November 15, 2011
Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignanciesMamta Gupta, Andrea E Wahner Hendrickson, Seong Seok Yun, et al.
NPJ Breast Cancer|December 19, 2023
Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancerSwaathi Jayaraman, Xinyan Wu, Krishna R Kalari, et al.
Cell Death and Differentiation|March 28, 2024
AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell deathJia Jia, Wenbo Ji, Antoine N Saliba, et al.
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