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Organic Letters|March 5, 2013
Asymmetric synthesis of cis-2,5-disubstituted pyrrolidine, the core scaffold of β3-AR agonistsFeng Xu, John Y L Chung, Jeffery C Moore, et al.ACS Central Science|December 29, 2021
Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19John A McIntosh, Tamas Benkovics, Steven M Silverman, et al.ACS Medicinal Chemistry Letters|July 24, 2018
Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of AsthmaXianhai Huang, Jason Brubaker, Wei Zhou, et al.Angewandte Chemie (International Ed. in English)|January 27, 2024
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to BelzutifanWai Ling Cheung-Lee, Joshua N Kolev, John A McIntosh, et al.Bioorganic & Medicinal Chemistry Letters|August 3, 2020
Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutesJian Liu, Deodial Guiadeen, Arto Krikorian, et al.Science (New York, N.Y.)|December 7, 2019
Design of an in vitro biocatalytic cascade for the manufacture of islatravirMark A Huffman, Anna Fryszkowska, Oscar Alvizo, et al.Science (New York, N.Y.)|May 7, 2026
Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitideArtis Klapars, Anna Fryszkowska, Stephanie Galanie, et al.Pageof 5