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Advances in Experimental Medicine and Biology|November 26, 2013
Hypoxia-directed drug strategies to target the tumor microenvironmentMichael P Hay, Kevin O Hicks, Jingli WangNeoplasia (New York, N.Y.)|December 29, 2018
An Intratumor Pharmacokinetic/Pharmacodynamic Model for the Hypoxia-Activated Prodrug Evofosfamide (TH-302): Monotherapy Activity is Not Dependent on a Bystander EffectCho Rong Hong, William R Wilson, Kevin O HicksFree Radical Biology & Medicine|October 4, 2014
Pharmacokinetic modeling of ascorbate diffusion through normal and tumor tissueCaroline Kuiper, Margreet C M Vissers, Kevin O HicksAdvances in Experimental Medicine and Biology|June 22, 2016
Efficient Protocol for the Identification of Hypoxic Cell RadiosensitisersCho Rong Hong, Jingli Wang, Kevin O Hicks, et al.Frontiers in Oncology|January 11, 2014
Design of optimized hypoxia-activated prodrugs using pharmacokinetic/pharmacodynamic modelingAnnika Foehrenbacher, Timothy W Secomb, William R Wilson, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|July 24, 2007
Analysis of the hypoxia-activated dinitrobenzamide mustard phosphate pre-prodrug PR-104 and its alcohol metabolite PR-104A in plasma and tissues by liquid chromatography-mass spectrometryKashyap Patel, David Lewiston, Yongchuan Gu, et al.Radiation Research|May 27, 2004
Oxygen dependence of the metabolic activation and cytotoxicity of tirapazamine: implications for extravascular transport and activity in tumorsKevin O Hicks, Bronwyn G Siim, Frederik B Pruijn, et al.Cancer Research|October 3, 2003
Multicellular resistance to tirapazamine is due to restricted extravascular transport: a pharmacokinetic/pharmacodynamic study in HT29 multicellular layer culturesKevin O Hicks, Frederik B Pruijn, Joanna R Sturman, et al.Journal of Pharmaceutical Sciences|September 13, 2014
Photodegradation of the benzotriazine 1,4-Di-N-oxide hypoxia-activated prodrug SN30000 in aqueous solutionYongchuan Gu, Jagdish K Jaiswal, Jingli Wang, et al.Cancer Biology & Therapy|May 28, 2019
Schedule-dependent potentiation of chemotherapy drugs by the hypoxia-activated prodrug SN30000Xinjian Mao, Sarah McManaway, Jagdish K Jaiswal, et al.Pageof 4