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Organic Letters|February 14, 2002
Oxabicyclo[3.2.1]octenes in organic synthesis: direct ring opening of oxabicyclo[3.2.1] ring systems with diisobutylaluminum hydride and a silyl ketene acetal--synthesis of the chiral C(19)-C(26) and C(27)-C(32) fragments of Scytophycin CKevin W Hunt, Paul A GriecoMolecular Metabolism|May 8, 2026
GPR75 Genetic Manipulations in Mice Reveal Central Mechanism for Weight Loss Independent of Developmental EffectsHua V Lin, Ibragim Gaidarov, Giuseppe Militello, et al.Organic Letters|October 30, 2009
Selective synthesis of 1-functionalized-alkyl-1H-indazolesKevin W Hunt, David A Moreno, Nicole Suiter, et al.Archives of Pharmacal Research|July 27, 2013
Qualification and application of a liquid chromatography-tandem mass spectrometric method for the determination of human Aβ1-40 and Aβ1-42 peptides in transgenic mouse plasma using micro-elution solid phase extractionYoung G Shin, Lee Hamm, Stanley Murakami, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 6, 2014
Elucidating the mechanism of cytochrome P450-mediated pyrimidine ring conversion to pyrazole metabolites with the BACE1 inhibitor GNE-892 in ratsRyan Takahashi, Shuguang Ma, Alan Deese, et al.European Journal of Drug Metabolism and Pharmacokinetics|April 4, 2014
Dose-dependent exposure and metabolism of GNE-892, a β-secretase inhibitor, in monkeys: contributions by P450, AO, and P-gpRyan Takahashi, Shuguang Ma, Qin Yue, et al.Bioorganic & Medicinal Chemistry Letters|May 1, 2014
Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitorsMatthew Volgraf, Lina Chan, Malcolm P Huestis, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2013
Mechanistic pharmacokinetic-pharmacodynamic modeling of BACE1 inhibition in monkeys: development of a predictive model for amyloid precursor protein processingXingrong Liu, Harvey Wong, Kimberly Scearce-Levie, et al.Journal of Medicinal Chemistry|November 21, 2014
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitorsAllen A Thomas, Kevin W Hunt, Brad Newhouse, et al.Journal of Medicinal Chemistry|March 30, 2013
Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher speciesKevin W Hunt, Adam W Cook, Ryan J Watts, et al.Pageof 2