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Kevin X Chen

Showing results (21-30 of 37) with videos related to

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Journal of Medicinal Chemistry|February 7, 2009
Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine proteaseKevin X Chen, Latha Nair, Bancha Vibulbhan, et al.
Journal of Medicinal Chemistry|December 24, 2008
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 proteaseSrikanth Venkatraman, Francisco Velazquez, Wanli Wu, et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|February 6, 2014
HIP1-ALK, a novel ALK fusion variant that responds to crizotinibDouglas D Fang, Bin Zhang, Qingyang Gu, et al.
Journal of Medicinal Chemistry|May 22, 2009
Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profilesStéphane L Bogen, Weidong Pan, Sumei Ruan, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2010
The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitorFrank Bennett, Yuhua Huang, Siska Hendrata, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of SCH 900188: A Potent Hepatitis C Virus NS5B Polymerase Inhibitor Prodrug As a Development CandidateKevin X Chen, Srikanth Venkatraman, Gopinadhan N Anilkumar, et al.
Bioorganic & Medicinal Chemistry|February 26, 2013
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymeraseSrikanth Venkatraman, Francisco Velazquez, Stephen Gavalas, et al.
Bioorganic & Medicinal Chemistry|November 27, 2013
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokineticsSrikanth Venkatraman, Francisco Velazquez, Stephen Gavalas, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
II. Novel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamidesGopinadhan N Anilkumar, Oleg Selyutin, Stuart B Rosenblum, et al.
Bioorganic & Medicinal Chemistry Letters|May 16, 2016
Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activityWensheng Yu, Craig A Coburn, De-Yi Yang, et al.
Pageof 4

Showing results (21-30 of 37) with videos related to

Sort By:
Pageof 4
Journal of Medicinal Chemistry|February 7, 2009
Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine proteaseKevin X Chen, Latha Nair, Bancha Vibulbhan, et al.
Journal of Medicinal Chemistry|December 24, 2008
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 proteaseSrikanth Venkatraman, Francisco Velazquez, Wanli Wu, et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|February 6, 2014
HIP1-ALK, a novel ALK fusion variant that responds to crizotinibDouglas D Fang, Bin Zhang, Qingyang Gu, et al.
Journal of Medicinal Chemistry|May 22, 2009
Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profilesStéphane L Bogen, Weidong Pan, Sumei Ruan, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2010
The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitorFrank Bennett, Yuhua Huang, Siska Hendrata, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of SCH 900188: A Potent Hepatitis C Virus NS5B Polymerase Inhibitor Prodrug As a Development CandidateKevin X Chen, Srikanth Venkatraman, Gopinadhan N Anilkumar, et al.
Bioorganic & Medicinal Chemistry|February 26, 2013
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymeraseSrikanth Venkatraman, Francisco Velazquez, Stephen Gavalas, et al.
Bioorganic & Medicinal Chemistry|November 27, 2013
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokineticsSrikanth Venkatraman, Francisco Velazquez, Stephen Gavalas, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
II. Novel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamidesGopinadhan N Anilkumar, Oleg Selyutin, Stuart B Rosenblum, et al.
Bioorganic & Medicinal Chemistry Letters|May 16, 2016
Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activityWensheng Yu, Craig A Coburn, De-Yi Yang, et al.
Pageof 4