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Assay and Drug Development Technologies|March 2, 2006
Evaluation of the rubidium efflux assay for preclinical identification of HERG blockadeKhuram W Chaudhary, Janet M O'Neal, Zun-Li Mo, et al.Frontiers in Pharmacology|April 1, 2025
<i>In silico</i> predictions of drug-induced changes in human cardiac contractility align with experimental recordingsCristian Trovato, Stefano Longobardi, Elisa Passini, et al.Journal of Pharmacological and Toxicological Methods|May 18, 2016
Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imagingGraham T Dempsey, Khuram W Chaudhary, Nicholas Atwater, et al.Journal of Molecular and Cellular Cardiology|January 22, 2004
Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardiumEric I Rossman, Rebecca E Petre, Khuram W Chaudhary, et al.Journal of the American College of Cardiology|August 18, 2004
Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heartKhuram W Chaudhary, Eric I Rossman, Valentino Piacentino, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|August 7, 2019
Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug DiscoveryNicole T Feric, Isabella Pallotta, Rishabh Singh, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|December 17, 2005
Embryonic stem cells in predictive cardiotoxicity: laser capture microscopy enables assay developmentKhuram W Chaudhary, Nestor X Barrezueta, Mary B Bauchmann, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|July 18, 2023
CardioMotion: identification of functional and structural cardiotoxic liabilities in small molecules through brightfield kinetic imagingWilliam Stebbeds, Kavita Raniga, David Standing, et al.Clinical and Translational Science|May 17, 2022
Cardiac sodium channel inhibition by lamotrigine: In vitro characterization and clinical implicationsLindsey Ingleby-Talecki, Sven C van Dijkman, Sean P Oosterholt, et al.Frontiers in Pharmacology|September 27, 2019
Considerations for an <i>In Vitro</i>, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-CardiomyocytesAlexandre J S Ribeiro, Brian D Guth, Michael Engwall, et al.Pageof 3