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Journal of Medicinal Chemistry|May 15, 2010
Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)Murielle M Véniant, Clarence Hale, Randall W Hungate, et al.Pageof 13