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Molecular Pharmaceutics
|
September 7, 2025
Canine Mdr1 Knockout MDCK Cells Reliably Estimate Human Small Intestinal Permeability (<i>P</i><sub>eff</sub>) and Fraction Absorbed (<i>f</i><sub>a</sub>)
Kristian Beran, Seong Hee Park, An Van den Bergh, et al.
Journal of Pharmaceutical Sciences
|
April 3, 2008
Formulation and in vivo evaluation of chlorpropham (CIPC) oral formulations
Philip J Kuehl, Tim Brenner, Parijat K Jain, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-<i>b</i>]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders
Christa C Chrovian, Akinola Soyode-Johnson, Brice Stenne, et al.
Journal of Medicinal Chemistry
|
December 7, 2017
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate
Christa C Chrovian, Akinola Soyode-Johnson, Alexander A Peterson, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor
Devin M Swanson, Brad M Savall, Kevin J Coe, et al.
Journal of Medicinal Chemistry
|
April 16, 2025
Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis
Olaf Kinzel, Steven D Goldberg, Maxwell D Cummings, et al.
European Journal of Pharmacology
|
May 18, 2011
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist
Michael P Maher, Anindya Bhattacharya, Hong Ao, et al.
Molecular Pharmacology
|
March 5, 2011
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor
Terrance D Barrett, Heather L Palomino, Theresa I Brondstetter, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2010
Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development
Michael A Letavic, Leah Aluisio, John R Atack, et al.
Journal of Medicinal Chemistry
|
October 31, 2022
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase
Mark S Tichenor, John J M Wiener, Navin L Rao, et al.
Page
of 2
Search research articles
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Showing results (11-20 of 20) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 20 results.
Molecular Pharmaceutics
|
September 7, 2025
Canine Mdr1 Knockout MDCK Cells Reliably Estimate Human Small Intestinal Permeability (<i>P</i><sub>eff</sub>) and Fraction Absorbed (<i>f</i><sub>a</sub>)
Kristian Beran, Seong Hee Park, An Van den Bergh, et al.
Journal of Pharmaceutical Sciences
|
April 3, 2008
Formulation and in vivo evaluation of chlorpropham (CIPC) oral formulations
Philip J Kuehl, Tim Brenner, Parijat K Jain, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-<i>b</i>]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders
Christa C Chrovian, Akinola Soyode-Johnson, Brice Stenne, et al.
Journal of Medicinal Chemistry
|
December 7, 2017
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate
Christa C Chrovian, Akinola Soyode-Johnson, Alexander A Peterson, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor
Devin M Swanson, Brad M Savall, Kevin J Coe, et al.
Journal of Medicinal Chemistry
|
April 16, 2025
Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis
Olaf Kinzel, Steven D Goldberg, Maxwell D Cummings, et al.
European Journal of Pharmacology
|
May 18, 2011
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist
Michael P Maher, Anindya Bhattacharya, Hong Ao, et al.
Molecular Pharmacology
|
March 5, 2011
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor
Terrance D Barrett, Heather L Palomino, Theresa I Brondstetter, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2010
Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development
Michael A Letavic, Leah Aluisio, John R Atack, et al.
Journal of Medicinal Chemistry
|
October 31, 2022
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase
Mark S Tichenor, John J M Wiener, Navin L Rao, et al.
Page
of 2