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Nature Protocols|August 15, 2025
Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editingNicolas Mathis, Kim Fabiano Marquart, Ahmed Allam, et al.Nature Communications|April 5, 2022
Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killingNina Frey, Luigi Tortola, David Egli, et al.Nature Biotechnology|January 16, 2023
Predicting prime editing efficiency and product purity by deep learningNicolas Mathis, Ahmed Allam, Lucas Kissling, et al.Nature Chemical Biology|September 21, 2023
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibilityLukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, et al.Elife|October 12, 2023
Mutant SF3B1 promotes malignancy in PDACPatrik Simmler, Eleonora I Ioannidi, Tamara Mengis, et al.Biotechnology and Bioengineering|March 19, 2019
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interferenceKai Xiong, Kim Fabiano Marquart, Karen Julie la Cour Karottki, et al.Nature Methods|September 23, 2024
Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAsKim Fabiano Marquart, Nicolas Mathis, Amina Mollaysa, et al.Cell Reports|August 24, 2022
SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancerPatrik Simmler, Cédric Cortijo, Lisa Maria Koch, et al.Pageof 1