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RSC Chemical Biology|June 5, 2026
A two-step bioconjugation of S. aureus lipoteichoic acid (LTA) affords fluorescent probes that illuminate the interaction between Gram-positive glycolipids and mammalian cell membranesJake Henry, Joe Nabarro, Harriet Chidwick, et al.
The Journal of Experimental Medicine|August 29, 2023
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosisKim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, et al.
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America|August 30, 2023
Extracorporeal Membrane Oxygenation-Dependent Fulminant Melioidosis From Caspase 4 Mutation Reversed by Interferon Gamma TherapyAseervatham Anusha Amali, Sharada Ravikumar, Wei Leong Chew, et al.
Science Immunology|August 26, 2018
Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular trapsKaiwen W Chen, Mercedes Monteleone, Dave Boucher, et al.
Life Science Alliance|August 9, 2023
Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzymeAmy H Chan, Sabrina S Burgener, Kassandra Vezyrgiannis, et al.
Journal of Immunology (Baltimore, Md. : 1950)|April 18, 2018
Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β SecretionKaiwen W Chen, Kate E Lawlor, Jessica B von Pein, et al.
Nature Communications|June 26, 2020
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteriaJosé Carlos Santos, Dave Boucher, Larisa Kapinos Schneider, et al.
The Journal of Investigative Dermatology|October 2, 2017
ENPP1 Mutation Causes Recessive Cole Disease by Altering MelanogenesisMarwa Chourabi, Mei Shan Liew, Shawn Lim, et al.
Nature Chemical Biology|May 16, 2019
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibitionRebecca C Coll, James R Hill, Christopher J Day, et al.
The Journal of Experimental Medicine|August 29, 2023
EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruptionMiriam Pinilla, Raoul Mazars, Romain Vergé, et al.
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