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Bioorganic & Medicinal Chemistry Letters|October 25, 2011
Novel tricyclic inhibitors of IKK2: discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066)Scott H Watterson, Charles M Langevine, Katy Van Kirk, et al.Biochemistry|August 25, 2004
Selective Itk inhibitors block T-cell activation and murine lung inflammationTai-An Lin, Kim W McIntyre, Jagabandhu Das, et al.Journal of Medicinal Chemistry|December 13, 2007
Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitorsJohn Hynes, Alaric J Dyckman, Shuqun Lin, et al.Journal of Medicinal Chemistry|June 17, 2016
Discovery and Structure-Activity Relationship (SAR) of a Series of Ethanolamine-Based Direct-Acting Agonists of Sphingosine-1-phosphate (S1P1)John L Gilmore, James E Sheppeck, Scott H Watterson, et al.Journal of Medicinal Chemistry|March 1, 2016
Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based SeriesScott H Watterson, Junqing Guo, Steve H Spergel, et al.Science Translational Medicine|July 26, 2019
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domainJames R Burke, Lihong Cheng, Kathleen M Gillooly, et al.ACS Medicinal Chemistry Letters|March 21, 2019
Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 InhibitorsChunjian Liu, James Lin, Ryan Moslin, et al.Bioorganic & Medicinal Chemistry Letters|April 9, 2016
Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)Junqing Guo, Scott H Watterson, Steven H Spergel, et al.Journal of Medicinal Chemistry|March 10, 2009
Novel tricyclic inhibitors of IkappaB kinaseJames Kempson, Steven H Spergel, Junqing Guo, et al.Journal of Medicinal Chemistry|May 17, 2002
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activityT G Murali Dhar, Zhongqi Shen, Junqing Guo, et al.Pageof 7