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Journal of Medicinal Chemistry|September 1, 2010
Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseasesChunjian Liu, James Lin, Stephen T Wrobleski, et al.Journal of Medicinal Chemistry|April 22, 2010
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)Scott H Watterson, Zili Xiao, Dharmpal S Dodd, et al.Journal of Medicinal Chemistry|July 19, 2019
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165Stephen T Wrobleski, Ryan Moslin, Shuqun Lin, et al.ACS Medicinal Chemistry Letters|March 18, 2016
Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical TrialsT G Murali Dhar, Hai-Yun Xiao, Jenny Xie, et al.Journal of Medicinal Chemistry|August 18, 2016
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)George V De Lucca, Qing Shi, Qingjie Liu, et al.Medchemcomm|August 16, 2018
Identification of potent tricyclic prodrug S1P1 receptor modulatorsDavid Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.Journal of Medicinal Chemistry|December 23, 2016
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P1 Receptor ModulatorMichael G Yang, Zili Xiao, T G Murali Dhar, et al.ACS Medicinal Chemistry Letters|November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTKAnurag S Srivastava, Soo Ko, Scott H Watterson, et al.Journal of Medicinal Chemistry|November 30, 2004
The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinaseKaterina Leftheris, Gulzar Ahmed, Ran Chan, et al.Journal of Medicinal Chemistry|February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical TrialsJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.Pageof 7