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PNAS Nexus|July 21, 2025
VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channelsAaron Kolski-Andreaco, Corina M Balut, Matthew D Green, et al.The Journal of Clinical Investigation|July 2, 2024
Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121Aaron Kolski-Andreaco, Stefanie Taiclet, Michael M Myerburg, et al.Plos One|January 3, 2018
Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytesAida Olivan-Viguera, Angel Luis Garcia-Otin, Javier Lozano-Gerona, et al.American Journal of Physiology. Cell Physiology|January 19, 2022
Histone deacetylase inhibitors (HDACi) increase expression of KCa2.3 (SK3) in primary microvascular endothelial cellsAaron Kolski-Andreaco, Corina M Balut, Claudia A Bertuccio, et al.International Journal of Molecular Sciences|March 13, 2019
KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal ContractilityMarta Sofía Valero, Mariano Ramón-Gimenez, Javier Lozano-Gerona, et al.Plos One|March 10, 2020
Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosisJavier Lozano-Gerona, Aida Oliván-Viguera, Pablo Delgado-Wicke, et al.Pageof 5