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Bioorganic & Medicinal Chemistry
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July 26, 2005
Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity
Aleem Gangjee, Yibin Zeng, Michael Ihnat, et al.
Cancer Research
|
January 1, 1989
Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts
J Thorndike, Y Gaumont, R L Kisliuk, et al.
Journal of Medicinal Chemistry
|
June 1, 1986
Synthesis and biological activity of resolved C-10 diastereomers of 10-methyl- and 10-ethyl-10-deazaminopterin
J I DeGraw, P H Christie, H Tagawa, et al.
Journal of Medicinal Chemistry
|
November 1, 1988
Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase
J R Piper, G S McCaleb, J A Montgomery, et al.
Biochemical Pharmacology
|
May 15, 1987
Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions
F M Sirotnak, L J Goutas, D M Jacobsen, et al.
Biophysical Journal
|
April 8, 2010
Dynamics of biological macromolecules: not a simple slaving by hydration water
S Khodadadi, J H Roh, A Kisliuk, et al.
Journal of Medicinal Chemistry
|
September 1, 1986
Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF)
M G Nair, N T Nanavati, I G Nair, et al.
Journal of Medicinal Chemistry
|
March 1, 1984
Synthesis and antifolate properties of 10-alkyl-8,10-dideazaminopterins
J I DeGraw, P H Christie, E G Brown, et al.
Journal of Medicinal Chemistry
|
June 1, 1989
Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds
S D Patil, C Jones, M G Nair, et al.
Journal of Medicinal Chemistry
|
January 1, 1988
Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative
J I DeGraw, W T Colwell, V H Brown, et al.
Page
of 16
Search research articles
Search
Showing results (101-110 of 152) with videos related to
Sort By:
Page
of 16
Bioorganic & Medicinal Chemistry
|
July 26, 2005
Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity
Aleem Gangjee, Yibin Zeng, Michael Ihnat, et al.
Cancer Research
|
January 1, 1989
Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts
J Thorndike, Y Gaumont, R L Kisliuk, et al.
Journal of Medicinal Chemistry
|
June 1, 1986
Synthesis and biological activity of resolved C-10 diastereomers of 10-methyl- and 10-ethyl-10-deazaminopterin
J I DeGraw, P H Christie, H Tagawa, et al.
Journal of Medicinal Chemistry
|
November 1, 1988
Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase
J R Piper, G S McCaleb, J A Montgomery, et al.
Biochemical Pharmacology
|
May 15, 1987
Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions
F M Sirotnak, L J Goutas, D M Jacobsen, et al.
Biophysical Journal
|
April 8, 2010
Dynamics of biological macromolecules: not a simple slaving by hydration water
S Khodadadi, J H Roh, A Kisliuk, et al.
Journal of Medicinal Chemistry
|
September 1, 1986
Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF)
M G Nair, N T Nanavati, I G Nair, et al.
Journal of Medicinal Chemistry
|
March 1, 1984
Synthesis and antifolate properties of 10-alkyl-8,10-dideazaminopterins
J I DeGraw, P H Christie, E G Brown, et al.
Journal of Medicinal Chemistry
|
June 1, 1989
Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds
S D Patil, C Jones, M G Nair, et al.
Journal of Medicinal Chemistry
|
January 1, 1988
Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative
J I DeGraw, W T Colwell, V H Brown, et al.
Page
of 16