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Expert Opinion on Drug Discovery|July 20, 2013
Predictive approaches to increase absorption of compounds during lead optimisationKlara Valko, James Butler, Peter Eddershaw
ADMET & DMPK|May 8, 2026
Linking biomimetic binding measurements to pharmacokinetic models of volume of distribution and hepatic clearanceKlara Valko
Progress in Medicinal Chemistry|March 19, 2019
Amyotrophic lateral sclerosisKlara Valko, Lukasz Ciesla
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|February 21, 2017
How to identify and eliminate compounds with a risk of high clinical dose during the early phase of lead optimisation in drug discoverySimon Teague, Klara Valko
ADMET & DMPK|March 18, 2022
Prediction of hERG inhibition of drug discovery compounds using biomimetic HPLC measurementsChrysanthos Stergiopoulos, Fotios Tsopelas, Klara Valko
ADMET & DMPK|March 18, 2022
Revisiting the application of Immobilized Artificial Membrane (IAM) chromatography to estimate <i>in vivo</i> distribution properties of drug discovery compounds based on the model of marketed drugsKlara Valko, Silvia Rava, Shenaz Bunally, et al.
Journal of Pharmaceutical Sciences|August 30, 2012
In vitro measurement of drug efficiency index to aid early lead optimizationKlara Valko, Elisabetta Chiarparin, Shenaz Nunhuck, et al.
ADMET & DMPK|November 11, 2024
Predicting the acute aquatic toxicity of organic UV filters used in cosmetic formulationsChrysanthos Stergiopoulos, Fotios Tsopelas, Maria Ochsenkühn-Petropoulou, et al.
Journal of Chromatography. A|September 19, 2002
Lipophilicity and pKa estimates from gradient high-performance liquid chromatographyRoman Kaliszan, Piotr Haber, Tomasz Baczek, et al.
Journal of Pharmaceutical Sciences|November 7, 2003
Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicityKlara Valko, Shenaz Nunhuck, Chris Bevan, et al.
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