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ACS Infectious Diseases|September 15, 2016
Glycogen Synthase Kinase 3β Promotes the Endocytosis of Transferrin in the African TrypanosomePaul J Guyett, Shuangluo Xia, David C Swinney, et al.
Frontiers in Drug Discovery|March 24, 2025
Multiparameter ranking of carbazoles for anti-trypanosome lead discoveryAmrita Sharma, Carlos E Sanz-Rodriguez, Michael P Pollastri, et al.
Plos One|February 26, 2013
Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffoldsSamiksha Katiyar, Irina Kufareva, Ranjan Behera, et al.
Molecular Pharmacology|May 23, 2022
Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug DevelopmentCarlos E Sanz-Rodríguez, Benjamin Hoffman, Paul J Guyett, et al.
Tetrahedron|May 9, 2020
Design, Synthesis, and Evaluation of Novel Anti-Trypanosomal CompoundsLance T Lepovitz, Alan R Meis, Sarah M Thomas, et al.
The Biochemical Journal|February 7, 2009
Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entitiesBhargavi Patham, Josh Duffy, Ariel Lane, et al.
Plos Neglected Tropical Diseases|March 5, 2016
A Four-Point Screening Method for Assessing Molecular Mechanism of Action (MMOA) Identifies Tideglusib as a Time-Dependent Inhibitor of Trypanosoma brucei GSK3βZachary T Swinney, Brad A Haubrich, Shuangluo Xia, et al.
ACS Medicinal Chemistry Letters|September 17, 2025
Optimization of Quinazolines for Inhibition of Trypanosoma brucei ProliferationSam Spijkers-Shaw, Pradip K Gadekar, Baljinder Singh, et al.
Journal of Medicinal Chemistry|April 20, 2013
Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasisGautam Patel, Caitlin E Karver, Ranjan Behera, et al.
Medchemcomm|February 17, 2015
EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIAJennifer L Woodring, Gautam Patel, Jessey Erath, et al.
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