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Regulatory Toxicology and Pharmacology : RTP
|
December 12, 2012
Determination of compound-specific acceptable daily intakes for 11 mutagenic carcinogens used in pharmaceutical synthesis
Patricia Ellis, Michelle Kenyon, Krista Dobo
Environmental and Molecular Mutagenesis
|
August 24, 2024
Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential
Jennifer Cheung, Krista Dobo, Shaofei Zhang, et al.
Science Advances
|
May 27, 2026
Complex versus simple <i>N</i>-nitrosamines: Comprehensive genotoxicity and in silico carcinogenicity assessment toward future testing paradigms
Xiaowen Sun, Maik Schuler, Shaofei Zhang, et al.
Regulatory Toxicology and Pharmacology : RTP
|
September 26, 2024
N-Nitrosamine drug substance related impurities (NDSRIs) - A proposal for the addition of subcategories to carcinogenic potency categorization approach categories 1 and 2 for NDSRIs with a molecular weight > 200 Da
Joel Bercu, Olivier Dirat, Krista Dobo, et al.
Regulatory Toxicology and Pharmacology : RTP
|
October 15, 2020
Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates
Catrin Hasselgren, Joel Bercu, Alex Cayley, et al.
Environmental and Molecular Mutagenesis
|
June 5, 2021
Permitted daily exposure limits for noteworthy N-nitrosamines
George E Johnson, Krista Dobo, Bhaskar Gollapudi, et al.
Regulatory Toxicology and Pharmacology : RTP
|
February 16, 2016
Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses
Alexander Amberg, Lisa Beilke, Joel Bercu, et al.
Regulatory Toxicology and Pharmacology : RTP
|
December 19, 2018
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses
Alexander Amberg, Roxanne V Andaya, Lennart T Anger, et al.
Regulatory Toxicology and Pharmacology : RTP
|
June 14, 2019
Genetic toxicology in silico protocol
Catrin Hasselgren, Ernst Ahlberg, Yumi Akahori, et al.
Regulatory Toxicology and Pharmacology : RTP
|
April 22, 2018
In silico toxicology protocols
Glenn J Myatt, Ernst Ahlberg, Yumi Akahori, et al.
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Search research articles
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
Regulatory Toxicology and Pharmacology : RTP
|
December 12, 2012
Determination of compound-specific acceptable daily intakes for 11 mutagenic carcinogens used in pharmaceutical synthesis
Patricia Ellis, Michelle Kenyon, Krista Dobo
Environmental and Molecular Mutagenesis
|
August 24, 2024
Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential
Jennifer Cheung, Krista Dobo, Shaofei Zhang, et al.
Science Advances
|
May 27, 2026
Complex versus simple <i>N</i>-nitrosamines: Comprehensive genotoxicity and in silico carcinogenicity assessment toward future testing paradigms
Xiaowen Sun, Maik Schuler, Shaofei Zhang, et al.
Regulatory Toxicology and Pharmacology : RTP
|
September 26, 2024
N-Nitrosamine drug substance related impurities (NDSRIs) - A proposal for the addition of subcategories to carcinogenic potency categorization approach categories 1 and 2 for NDSRIs with a molecular weight > 200 Da
Joel Bercu, Olivier Dirat, Krista Dobo, et al.
Regulatory Toxicology and Pharmacology : RTP
|
October 15, 2020
Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates
Catrin Hasselgren, Joel Bercu, Alex Cayley, et al.
Environmental and Molecular Mutagenesis
|
June 5, 2021
Permitted daily exposure limits for noteworthy N-nitrosamines
George E Johnson, Krista Dobo, Bhaskar Gollapudi, et al.
Regulatory Toxicology and Pharmacology : RTP
|
February 16, 2016
Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses
Alexander Amberg, Lisa Beilke, Joel Bercu, et al.
Regulatory Toxicology and Pharmacology : RTP
|
December 19, 2018
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses
Alexander Amberg, Roxanne V Andaya, Lennart T Anger, et al.
Regulatory Toxicology and Pharmacology : RTP
|
June 14, 2019
Genetic toxicology in silico protocol
Catrin Hasselgren, Ernst Ahlberg, Yumi Akahori, et al.
Regulatory Toxicology and Pharmacology : RTP
|
April 22, 2018
In silico toxicology protocols
Glenn J Myatt, Ernst Ahlberg, Yumi Akahori, et al.
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of 1