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Kristian Birchall

Showing results (11-20 of 31) with videos related to

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Drug Discovery Today|September 13, 2020
Fragment-based target screening as an empirical approach to prioritising targets: a case study on antibacterialsPeter Canning, Kristian Birchall, Catherine A Kettleborough, et al.
Frontiers in Molecular Neuroscience|April 30, 2024
Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?Sandra Kuemper, Andrew G Cairns, Kristian Birchall, et al.
Journal of Chemical Information and Modeling|May 2, 2022
Incorporating Target-Specific Pharmacophoric Information into Deep Generative Models for Fragment ElaborationThomas E Hadfield, Fergus Imrie, Andy Merritt, et al.
ACS Chemical Biology|October 18, 2014
Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD fingerThomas C R Miller, Trevor J Rutherford, Kristian Birchall, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV‑2 NSP14Elliott B Smyth, João P Pisco, Kristian Birchall, et al.
BMJ Open|June 25, 2013
Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assayJuan D Guzman, Dimitrios Evangelopoulos, Antima Gupta, et al.
Bioorganic & Medicinal Chemistry Letters|December 18, 2018
Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1Joanne Osborne, Kristian Birchall, Denise J Tsagris, et al.
Scientific Reports|June 11, 2023
Identification of novel p-cresol inhibitors that reduce Clostridioides difficile's ability to compete with species of the gut microbiomeMark A Harrison, Rebecca J Farthing, Nyasha Allen, et al.
Journal of Medicinal Chemistry|April 3, 2014
Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)Timothy M Chapman, Simon A Osborne, Claire Wallace, et al.
Journal of Medicinal Chemistry|April 28, 2018
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization PlatformShishir M Pant, Amanda Mukonoweshuro, Bimbisar Desai, et al.
Pageof 4

Showing results (11-20 of 31) with videos related to

Sort By:
Pageof 4
Drug Discovery Today|September 13, 2020
Fragment-based target screening as an empirical approach to prioritising targets: a case study on antibacterialsPeter Canning, Kristian Birchall, Catherine A Kettleborough, et al.
Frontiers in Molecular Neuroscience|April 30, 2024
Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?Sandra Kuemper, Andrew G Cairns, Kristian Birchall, et al.
Journal of Chemical Information and Modeling|May 2, 2022
Incorporating Target-Specific Pharmacophoric Information into Deep Generative Models for Fragment ElaborationThomas E Hadfield, Fergus Imrie, Andy Merritt, et al.
ACS Chemical Biology|October 18, 2014
Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD fingerThomas C R Miller, Trevor J Rutherford, Kristian Birchall, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV‑2 NSP14Elliott B Smyth, João P Pisco, Kristian Birchall, et al.
BMJ Open|June 25, 2013
Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assayJuan D Guzman, Dimitrios Evangelopoulos, Antima Gupta, et al.
Bioorganic & Medicinal Chemistry Letters|December 18, 2018
Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1Joanne Osborne, Kristian Birchall, Denise J Tsagris, et al.
Scientific Reports|June 11, 2023
Identification of novel p-cresol inhibitors that reduce Clostridioides difficile's ability to compete with species of the gut microbiomeMark A Harrison, Rebecca J Farthing, Nyasha Allen, et al.
Journal of Medicinal Chemistry|April 3, 2014
Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)Timothy M Chapman, Simon A Osborne, Claire Wallace, et al.
Journal of Medicinal Chemistry|April 28, 2018
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization PlatformShishir M Pant, Amanda Mukonoweshuro, Bimbisar Desai, et al.
Pageof 4