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Science Advances|November 9, 2022
Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicitiesJohan K E Spetz, Mary H C Florido, Cameron S Fraser, et al.Cancer Research|March 29, 2014
Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancersAaron N Hata, Alan Yeo, Anthony C Faber, et al.Cell|February 28, 2015
Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapyJoan Montero, Kristopher A Sarosiek, Joseph D DeAngelo, et al.Nature Communications|October 2, 2022
Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimeticsCameron S Fraser, Johan K E Spetz, Xingping Qin, et al.Nature Chemical Biology|March 14, 2024
Functional genomic screens with death rate analyses reveal mechanisms of drug actionMegan E Honeywell, Marie S Isidor, Nicholas W Harper, et al.Nature Communications|October 26, 2017
BCL-XL directly modulates RAS signalling to favour cancer cell stemnessSophie de Carné Trécesson, Frédérique Souazé, Agnès Basseville, et al.Nature Communications|July 30, 2025
De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancerHuan Zhang, Naiara Santana-Codina, Qijia Yu, et al.Proceedings of the National Academy of Sciences of the United States of America|October 3, 2013
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistanceNeil Johnson, Shawn F Johnson, Wei Yao, et al.The EMBO Journal|January 15, 2024
In situ architecture of Opa1-dependent mitochondrial cristae remodelingMichelle Y Fry, Paula P Navarro, Pusparanee Hakim, et al.Nature Communications|October 14, 2025
A molecular circuit regulates fate plasticity in emerging and adult AT2 cellsAmitoj S Sawhney, Brian J Deskin, Junming Cai, et al.Pageof 7