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Kyle A Emmitte

Showing results (21-30 of 70) with videos related to

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Journal of Medicinal Chemistry|December 14, 2011
Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discoveryBruce J Melancon, Corey R Hopkins, Michael R Wood, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2009
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5Andrew S Felts, Sam A Saleh, Uyen Le, et al.
Biorxiv : the Preprint Server for Biology|July 16, 2025
Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14Percy S Agogo-Mawuli, Isra Sadiya, Tigran M Abramyan, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 14, 2015
Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinctionAdam G Walker, Cody J Wenthur, Zixiu Xiang, et al.
ACS Chemical Neuroscience|May 7, 2014
A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptorsHyekyung P Cho, Darren W Engers, Daryl F Venable, et al.
The Journal of Biological Chemistry|August 23, 2025
Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14Percy S Agogo-Mawuli, Isra Sadiya, Tigran M Abramyan, et al.
Biorxiv : the Preprint Server for Biology|October 24, 2023
Heterozygous expression of a <i>Kcnt1</i> gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neuronsAmy N Shore, Keyong Li, Mona Safari, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2011
Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathwayJimmy R Theriault, Andrew S Felts, Brittney S Bates, et al.
Journal of Medicinal Chemistry|May 31, 2013
Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM)Cody J Wenthur, Ryan Morrison, Andrew S Felts, et al.
ACS Chemical Neuroscience|November 4, 2020
VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical NeuronsBrittany D Spitznagel, Nigam M Mishra, Alshaima'a M Qunies, et al.
Pageof 7

Showing results (21-30 of 70) with videos related to

Sort By:
Pageof 7
Journal of Medicinal Chemistry|December 14, 2011
Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discoveryBruce J Melancon, Corey R Hopkins, Michael R Wood, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2009
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5Andrew S Felts, Sam A Saleh, Uyen Le, et al.
Biorxiv : the Preprint Server for Biology|July 16, 2025
Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14Percy S Agogo-Mawuli, Isra Sadiya, Tigran M Abramyan, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 14, 2015
Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinctionAdam G Walker, Cody J Wenthur, Zixiu Xiang, et al.
ACS Chemical Neuroscience|May 7, 2014
A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptorsHyekyung P Cho, Darren W Engers, Daryl F Venable, et al.
The Journal of Biological Chemistry|August 23, 2025
Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14Percy S Agogo-Mawuli, Isra Sadiya, Tigran M Abramyan, et al.
Biorxiv : the Preprint Server for Biology|October 24, 2023
Heterozygous expression of a <i>Kcnt1</i> gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neuronsAmy N Shore, Keyong Li, Mona Safari, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2011
Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathwayJimmy R Theriault, Andrew S Felts, Brittney S Bates, et al.
Journal of Medicinal Chemistry|May 31, 2013
Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM)Cody J Wenthur, Ryan Morrison, Andrew S Felts, et al.
ACS Chemical Neuroscience|November 4, 2020
VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical NeuronsBrittany D Spitznagel, Nigam M Mishra, Alshaima'a M Qunies, et al.
Pageof 7