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Bioorganic & Medicinal Chemistry Letters
|
March 19, 2016
N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Biorxiv : the Preprint Server for Biology
|
March 3, 2025
Phenethylaminylation: Preliminary <i>In Vitro</i> Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound
Rajiv S Rangan, R Max Petty, Suchismita Acharya, et al.
ACS Chemical Neuroscience
|
May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction
Russell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5
Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats
Kimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
September 23, 2014
Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles
Jerri M Rook, Mohammed N Tantawy, Mohammad S Ansari, et al.
Journal of Medicinal Chemistry
|
October 24, 2018
Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu<sub>2</sub>) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores
Elizabeth S Childress, Joshua M Wieting, Andrew S Felts, et al.
Molecular Pharmacology
|
August 7, 2012
Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships
Karen J Gregory, Meredith J Noetzel, Jerri M Rook, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
July 1, 2017
Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation
Adam G Walker, Douglas J Sheffler, Andrew S Lewis, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 1, 2013
Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Page
of 7
Search research articles
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Showing results (41-50 of 70) with videos related to
Sort By:
Page
of 7
Bioorganic & Medicinal Chemistry Letters
|
March 19, 2016
N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Biorxiv : the Preprint Server for Biology
|
March 3, 2025
Phenethylaminylation: Preliminary <i>In Vitro</i> Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound
Rajiv S Rangan, R Max Petty, Suchismita Acharya, et al.
ACS Chemical Neuroscience
|
May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction
Russell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5
Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats
Kimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
September 23, 2014
Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles
Jerri M Rook, Mohammed N Tantawy, Mohammad S Ansari, et al.
Journal of Medicinal Chemistry
|
October 24, 2018
Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu<sub>2</sub>) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores
Elizabeth S Childress, Joshua M Wieting, Andrew S Felts, et al.
Molecular Pharmacology
|
August 7, 2012
Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships
Karen J Gregory, Meredith J Noetzel, Jerri M Rook, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
July 1, 2017
Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation
Adam G Walker, Douglas J Sheffler, Andrew S Lewis, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 1, 2013
Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Page
of 7