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ACS Medicinal Chemistry Letters
|
September 27, 2017
Design and Synthesis of mGlu<sub>2</sub> NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core
Katrina A Bollinger, Andrew S Felts, Christopher J Brassard, et al.
ACS Chemical Neuroscience
|
February 18, 2014
Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site
Karen J Gregory, Elizabeth D Nguyen, Chrysa Malosh, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2014
Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety
Brittney S Bates, Alice L Rodriguez, Andrew S Felts, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 30, 2017
Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Journal of Medicinal Chemistry
|
November 3, 2015
Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2
Andrew S Felts, Alice L Rodriguez, Katrina A Smith, et al.
ACS Chemical Neuroscience
|
August 8, 2018
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M<sub>1</sub> Positive Allosteric Modulators
Julie L Engers, Aaron M Bender, Jacob J Kalbfleisch, et al.
Journal of Medicinal Chemistry
|
September 4, 2015
Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents
Julie L Engers, Alice L Rodriguez, Leah C Konkol, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design and Synthesis of <i>N</i>-Aryl Phenoxyethoxy Pyridinones as Highly Selective and CNS Penetrant mGlu<sub>3</sub> NAMs
Julie L Engers, Katrina A Bollinger, Rebecca L Weiner, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 28, 2015
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 23, 2008
Discovery of thiophene inhibitors of polo-like kinase
Kyle A Emmitte, C Webb Andrews, Jennifer G Badiang, et al.
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of 7
Search research articles
Search
Showing results (51-60 of 70) with videos related to
Sort By:
Page
of 7
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design and Synthesis of mGlu<sub>2</sub> NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core
Katrina A Bollinger, Andrew S Felts, Christopher J Brassard, et al.
ACS Chemical Neuroscience
|
February 18, 2014
Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site
Karen J Gregory, Elizabeth D Nguyen, Chrysa Malosh, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2014
Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety
Brittney S Bates, Alice L Rodriguez, Andrew S Felts, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 30, 2017
Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Journal of Medicinal Chemistry
|
November 3, 2015
Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2
Andrew S Felts, Alice L Rodriguez, Katrina A Smith, et al.
ACS Chemical Neuroscience
|
August 8, 2018
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M<sub>1</sub> Positive Allosteric Modulators
Julie L Engers, Aaron M Bender, Jacob J Kalbfleisch, et al.
Journal of Medicinal Chemistry
|
September 4, 2015
Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents
Julie L Engers, Alice L Rodriguez, Leah C Konkol, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design and Synthesis of <i>N</i>-Aryl Phenoxyethoxy Pyridinones as Highly Selective and CNS Penetrant mGlu<sub>3</sub> NAMs
Julie L Engers, Katrina A Bollinger, Rebecca L Weiner, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 28, 2015
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 23, 2008
Discovery of thiophene inhibitors of polo-like kinase
Kyle A Emmitte, C Webb Andrews, Jennifer G Badiang, et al.
Page
of 7