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Journal of Medicinal Chemistry|November 20, 2014
Selective inhibitors of protein methyltransferasesH Ümit Kaniskan, Kyle D Konze, Jian JinBlood|January 9, 2015
Polycomb genes, miRNA, and their deregulation in B-cell malignanciesGang Greg Wang, Kyle D Konze, Jianguo TaoExperimental Hematology|June 2, 2015
Targeting EZH2 and PRC2 dependence as novel anticancer therapyBowen Xu, Kyle D Konze, Jian Jin, et al.Journal of Chemical Information and Modeling|June 3, 2020
Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and OptimizationPhani Ghanakota, Pieter H Bos, Kyle D Konze, et al.Journal of Chemical Information and Modeling|August 13, 2019
Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 InhibitorsKyle D Konze, Pieter H Bos, Markus K Dahlgren, et al.Chemmedchem|January 21, 2014
A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9aKyle D Konze, Samantha G Pattenden, Feng Liu, et al.Journal of Medicinal Chemistry|July 29, 2016
Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) InhibitorsXiaobao Yang, Fengling Li, Kyle D Konze, et al.Iscience|July 24, 2019
Multi-omic Dissection of Oncogenically Active Epiproteomes Identifies Drivers of Proliferative and Invasive Breast TumorsJohn A Wrobel, Ling Xie, Li Wang, et al.Blood|November 15, 2014
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemiaBowen Xu, Doan M On, Anqi Ma, et al.ACS Chemical Biology|April 26, 2013
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1Kyle D Konze, Anqi Ma, Fengling Li, et al.Pageof 2