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Journal of Medicinal Chemistry|February 20, 2015
The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activityBenjamin A Seigal, William H Connors, Andrew Fraley, et al.
Molecular Pharmacology|November 3, 2007
Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumorsStuart L Emanuel, Terry V Hughes, Mary Adams, et al.
Bioorganic & Medicinal Chemistry Letters|May 30, 2008
Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinasesGuozhang Xu, Lily Lee Searle, Terry V Hughes, et al.
Journal of Palliative Medicine|September 1, 2021
Exploring the Psychological Aspects of Palliative Care: Lessons Learned from an Interdisciplinary Seminar of ExpertsKeri O Brenner, Leah B Rosenberg, Margaret A Cramer, et al.
Kidney International|December 4, 2019
The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trialErik J M van Bommel, Marcel H A Muskiet, Michaël J B van Baar, et al.
Structure (London, England : 1993)|February 14, 2012
Structures of adnectin/protein complexes reveal an expanded binding footprintVidhyashankar Ramamurthy, Stanley R Krystek, Alexander Bush, et al.
Mabs|November 25, 2010
A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptorStuart L Emanuel, Linda J Engle, Ginger Chao, et al.
Leukemia|October 22, 2011
Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2A V Purandare, T M McDevitt, H Wan, et al.
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