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The Journal of Pharmacology and Experimental Therapeutics|August 12, 2004
Effect of cell cycle inhibition on Cisplatin-induced cytotoxicityMelissa L Fishel, David R Newell, Roger J Griffin, et al.
Molecular Cancer Therapeutics|August 16, 2019
Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder CancerMelissa L Fishel, Hanyu Xia, Jack McGeown, et al.
Redox Biology|September 3, 2025
The absence of Peroxiredoxin-1 in human pancreatic ductal adenocarcinoma (PDAC) markedly reduces cell survival and tumor growth when coupled with the inhibition of Ref-1 redox signalingSonia Kiran, Randall S Wireman, Jacqueline Peil, et al.
Molecular Cancer Therapeutics|August 19, 2016
Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer ModelsDerek P Logsdon, Michelle Grimard, Meihua Luo, et al.
Research Square|January 9, 2026
Targeting APE1 endonuclease activity impairs metastasis and enhances genotoxic therapy response in pancreatic cancerEyram K Kpenu, Mahmut Mijiti, Silpa Gampala, et al.
The Journal of Biological Chemistry|December 11, 2014
Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2Melissa L Fishel, Xue Wu, Cecilia M Devlin, et al.
Pancreas|November 20, 2014
Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG MiceHarlan E Shannon, Melissa L Fishel, Jingwu Xie, et al.
ACS Chemical Biology|April 4, 2020
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic DataDavid Xu, Donghui Zhou, Khuchtumur Bum-Erdene, et al.
Journal of Experimental & Clinical Cancer Research : CR|August 11, 2021
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential targetSilpa Gampala, Fenil Shah, Xiaoyu Lu, et al.
Cancer Research|April 3, 2020
Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination ImmunotherapyDaniel R Principe, Matthew Narbutis, Sandeep Kumar, et al.
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