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International Journal of Cancer|May 20, 1998
Potent antitumor activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine in choriocarcinoma-bearing ratsS Hatse, L Naesens, B Degrève, et al.
AIDS (London, England)|January 1, 1991
9-(2-Phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeysJ Balzarini, L Naesens, J Slachmuylders, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 9, 1996
Mechanism of anti-HIV action of masked alaninyl d4T-MP derivativesJ Balzarini, A Karlsson, S Aquaro, et al.
Pharmaceutical Research|August 26, 1998
Carrier mechanisms involved in the transepithelial transport of bis(POM)-PMEA and its metabolites across Caco-2 monolayersP Annaert, J Van Gelder, L Naesens, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 19, 2002
Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixturesJ van Gelder, S Deferme, L Naesens, et al.
Pharmaceutical Research|August 18, 1999
Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oral absorption: an in vitro studyJ Van Gelder, P Annaert, L Naesens, et al.
Antimicrobial Agents and Chemotherapy|February 25, 2005
Antiadenovirus activities of several classes of nucleoside and nucleotide analoguesL Naesens, L Lenaerts, G Andrei, et al.
AAPS Pharmsci|November 9, 2002
Role of MRP4 and MRP5 in biology and chemotherapyJ Sampath, M Adachi, S Hatse, et al.
Molecular Pharmacology|September 25, 1999
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudineD Saboulard, L Naesens, D Cahard, et al.
Biochemical Pharmacology|July 6, 1993
Metabolism and pharmacokinetics of the anti-HIV-1-specific inhibitor [1-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3-N- methyl-thymine]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dio xide)J Balzarini, L Naesens, C Bohman, et al.
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