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The Journal of Pharmacology and Experimental Therapeutics
|
February 1, 2017
Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive <i>N</i>-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression
J M Witkin, S N Mitchell, K A Wafford, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 13, 2006
Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo
Brianne Weiss, Andrew Alt, Ann Marie Ogden, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 22, 2005
Synthesis and structure-activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor
Qing Shi, Paul L Ornstein, Karin Briner, et al.
Journal of Medicinal Chemistry
|
September 20, 2002
Ethyl (3S,4aR,6S,8aR)-6-(4-ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso-quinoline-3-carboxylic ester: a prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine
Sandra A Filla, Mark A Winter, Kirk W Johnson, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 27, 2019
Modulation of TARP <i>γ</i>8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain
Kelly L Knopp, Rosa Maria A Simmons, Wenhong Guo, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2013
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models
Jose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.
Journal of Medicinal Chemistry
|
January 23, 2004
Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor
Timothy I Richardson, Paul L Ornstein, Karin Briner, et al.
Nature Medicine
|
November 8, 2016
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy
Jose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.
Journal of Medicinal Chemistry
|
June 25, 2005
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain
Esteban Dominguez, Smriti Iyengar, Harlan E Shannon, et al.
Page
of 24
Search research articles
Search
Showing results (221-230 of 233) with videos related to
Sort By:
Page
of 24
The Journal of Pharmacology and Experimental Therapeutics
|
February 1, 2017
Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive <i>N</i>-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression
J M Witkin, S N Mitchell, K A Wafford, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 13, 2006
Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo
Brianne Weiss, Andrew Alt, Ann Marie Ogden, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 22, 2005
Synthesis and structure-activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor
Qing Shi, Paul L Ornstein, Karin Briner, et al.
Journal of Medicinal Chemistry
|
September 20, 2002
Ethyl (3S,4aR,6S,8aR)-6-(4-ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso-quinoline-3-carboxylic ester: a prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine
Sandra A Filla, Mark A Winter, Kirk W Johnson, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 27, 2019
Modulation of TARP <i>γ</i>8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain
Kelly L Knopp, Rosa Maria A Simmons, Wenhong Guo, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2013
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models
Jose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.
Journal of Medicinal Chemistry
|
January 23, 2004
Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor
Timothy I Richardson, Paul L Ornstein, Karin Briner, et al.
Nature Medicine
|
November 8, 2016
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy
Jose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.
Journal of Medicinal Chemistry
|
June 25, 2005
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain
Esteban Dominguez, Smriti Iyengar, Harlan E Shannon, et al.
Page
of 24