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Journal of Medicinal Chemistry
|
January 14, 2017
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
James R Corte, Tianan Fang, Honey Osuna, et al.
Journal of Medicinal Chemistry
|
March 18, 2005
Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor
Mimi L Quan, Patrick Y S Lam, Qi Han, et al.
The Journal of Investigative Dermatology
|
September 6, 2017
Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure
Alexandra M Haugh, Bin Zhang, Victor L Quan, et al.
ACS Medicinal Chemistry Letters
|
May 26, 2015
Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety
Zilun Hu, Pancras C Wong, Paul J Gilligan, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 12, 2006
Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties
Donald J P Pinto, Robert A Galemmo, Mimi L Quan, et al.
Journal of Medicinal Chemistry
|
February 15, 2001
Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa
D J Pinto, M J Orwat, S Wang, et al.
Bioorganic & Medicinal Chemistry
|
April 14, 2016
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
James R Corte, Tianan Fang, Donald J P Pinto, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2017
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
James R Corte, Wu Yang, Tianan Fang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Zilun Hu, Cailan Wang, Peter W Glunz, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors
Mimi L Quan, Pancras C Wong, Cailan Wang, et al.
Page
of 26
Search research articles
Search
Showing results (241-250 of 258) with videos related to
Sort By:
Page
of 26
Journal of Medicinal Chemistry
|
January 14, 2017
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
James R Corte, Tianan Fang, Honey Osuna, et al.
Journal of Medicinal Chemistry
|
March 18, 2005
Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor
Mimi L Quan, Patrick Y S Lam, Qi Han, et al.
The Journal of Investigative Dermatology
|
September 6, 2017
Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure
Alexandra M Haugh, Bin Zhang, Victor L Quan, et al.
ACS Medicinal Chemistry Letters
|
May 26, 2015
Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety
Zilun Hu, Pancras C Wong, Paul J Gilligan, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 12, 2006
Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties
Donald J P Pinto, Robert A Galemmo, Mimi L Quan, et al.
Journal of Medicinal Chemistry
|
February 15, 2001
Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa
D J Pinto, M J Orwat, S Wang, et al.
Bioorganic & Medicinal Chemistry
|
April 14, 2016
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
James R Corte, Tianan Fang, Donald J P Pinto, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2017
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
James R Corte, Wu Yang, Tianan Fang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Zilun Hu, Cailan Wang, Peter W Glunz, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors
Mimi L Quan, Pancras C Wong, Cailan Wang, et al.
Page
of 26