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L Rigat

Showing results (1-10 of 10) with videos related to

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Analytical Biochemistry|October 24, 2006
A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymeraseYing-Kai Wang, Karen L Rigat, Susan B Roberts, et al.
Archives of Biochemistry and Biophysics|December 8, 2007
RNA template-mediated inhibition of hepatitis C virus RNA-dependent RNA polymerase activityYing-Kai Wang, Karen L Rigat, Jin-Hua Sun, et al.
Journal of Virology|January 7, 2000
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virusG Luo, R K Hamatake, D M Mathis, et al.
Organic & Biomolecular Chemistry|July 30, 2011
The synthesis of novel heteroaryl-fused 7,8,9,10-tetrahydro-6H-azepino[1,2-a]indoles, 4-oxo-2,3-dihydro-1H-[1,4]diazepino[1,7-a]indoles and 1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indoles. Effective inhibitors of HCV NS5B polymeraseMin Ding, Feng He, Michael A Poss, et al.
Bioorganic & Medicinal Chemistry Letters|January 10, 2016
Discovery and preclinical evaluation of potent, orally bioavailable, metabolically stable cyclopropylindolobenzazepine acylsulfonamides as thumb site 1 inhibitors of the hepatitis c virus NS5B RNA-dependent, RNA polymerasePiyasena Hewawasam, Yong Tu, Min Gao, et al.
The Journal of Biological Chemistry|October 11, 2014
Mechanism of inhibition for BMS-791325, a novel non-nucleoside inhibitor of hepatitis C virus NS5B polymeraseKaren L Rigat, Hao Lu, Ying-Kai Wang, et al.
Antimicrobial Agents and Chemotherapy|April 16, 2014
Preclinical characterization of BMS-791325, an allosteric inhibitor of hepatitis C Virus NS5B polymeraseJulie A Lemm, Mengping Liu, Robert G Gentles, et al.
Bioorganic & Medicinal Chemistry Letters|March 20, 2012
Synthesis and SAR studies of novel heteroaryl fused tetracyclic indole-diamide compounds: potent allosteric inhibitors of the hepatitis C virus NS5B polymeraseMin Ding, Feng He, Thomas W Hudyma, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymeraseBarbara Zhizhen Zheng, Stanley V D'Andrea, Umesh Hanumegowda, et al.
Bioorganic & Medicinal Chemistry Letters|April 14, 2011
Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virusXiaofan Zheng, Thomas W Hudyma, Scott W Martin, et al.
Pageof 1

Showing results (1-10 of 10) with videos related to

Sort By:
Pageof 1
Analytical Biochemistry|October 24, 2006
A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymeraseYing-Kai Wang, Karen L Rigat, Susan B Roberts, et al.
Archives of Biochemistry and Biophysics|December 8, 2007
RNA template-mediated inhibition of hepatitis C virus RNA-dependent RNA polymerase activityYing-Kai Wang, Karen L Rigat, Jin-Hua Sun, et al.
Journal of Virology|January 7, 2000
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virusG Luo, R K Hamatake, D M Mathis, et al.
Organic & Biomolecular Chemistry|July 30, 2011
The synthesis of novel heteroaryl-fused 7,8,9,10-tetrahydro-6H-azepino[1,2-a]indoles, 4-oxo-2,3-dihydro-1H-[1,4]diazepino[1,7-a]indoles and 1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indoles. Effective inhibitors of HCV NS5B polymeraseMin Ding, Feng He, Michael A Poss, et al.
Bioorganic & Medicinal Chemistry Letters|January 10, 2016
Discovery and preclinical evaluation of potent, orally bioavailable, metabolically stable cyclopropylindolobenzazepine acylsulfonamides as thumb site 1 inhibitors of the hepatitis c virus NS5B RNA-dependent, RNA polymerasePiyasena Hewawasam, Yong Tu, Min Gao, et al.
The Journal of Biological Chemistry|October 11, 2014
Mechanism of inhibition for BMS-791325, a novel non-nucleoside inhibitor of hepatitis C virus NS5B polymeraseKaren L Rigat, Hao Lu, Ying-Kai Wang, et al.
Antimicrobial Agents and Chemotherapy|April 16, 2014
Preclinical characterization of BMS-791325, an allosteric inhibitor of hepatitis C Virus NS5B polymeraseJulie A Lemm, Mengping Liu, Robert G Gentles, et al.
Bioorganic & Medicinal Chemistry Letters|March 20, 2012
Synthesis and SAR studies of novel heteroaryl fused tetracyclic indole-diamide compounds: potent allosteric inhibitors of the hepatitis C virus NS5B polymeraseMin Ding, Feng He, Thomas W Hudyma, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymeraseBarbara Zhizhen Zheng, Stanley V D'Andrea, Umesh Hanumegowda, et al.
Bioorganic & Medicinal Chemistry Letters|April 14, 2011
Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virusXiaofan Zheng, Thomas W Hudyma, Scott W Martin, et al.
Pageof 1