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Biopharmaceutics & Drug Disposition
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February 24, 2023
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT<sub>6</sub> receptor occupancy from non-human primates to humans
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
May 21, 2016
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme
Laigao Chen, Nabeel Nabulsi, Mika Naganawa, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
December 12, 2018
Quantitative Analysis of <sup>18</sup>F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
Akihiro Takano, Laigao Chen, Sangram Nag, et al.
Journal of Medicinal Chemistry
|
October 18, 2022
Imaging Leucine-Rich Repeat Kinase 2 In Vivo with <sup>18</sup>F-Labeled Positron Emission Tomography Ligand
Zhen Chen, Jiahui Chen, Laigao Chen, et al.
Journal of Medicinal Chemistry
|
May 9, 2013
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand
Lei Zhang, Anabella Villalobos, Elizabeth M Beck, et al.
Nuclear Medicine and Biology
|
May 11, 2012
The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)
Marc B Skaddan, Lei Zhang, Douglas S Johnson, et al.
Molecular Imaging and Biology
|
June 18, 2021
Preclinical Evaluation of <sup>89</sup>Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy
Kevin P Maresca, Jianqing Chen, Divya Mathur, et al.
Clinical Pharmacology and Therapeutics
|
May 19, 2019
Positron Emission Tomography Imaging of [<sup>11</sup> C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A
Sarah Billington, Steven Shoner, Scott Lee, et al.
Journal of Medicinal Chemistry
|
January 23, 2018
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain
Lei Zhang, Laigao Chen, Jason K Dutra, et al.
Science Translational Medicine
|
August 17, 2022
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease
Ashwin V Venkataraman, Ayla Mansur, Gaia Rizzo, et al.
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of 3
Search research articles
Search
Showing results (11-20 of 28) with videos related to
Sort By:
Page
of 3
Biopharmaceutics & Drug Disposition
|
February 24, 2023
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT<sub>6</sub> receptor occupancy from non-human primates to humans
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
May 21, 2016
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme
Laigao Chen, Nabeel Nabulsi, Mika Naganawa, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
December 12, 2018
Quantitative Analysis of <sup>18</sup>F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
Akihiro Takano, Laigao Chen, Sangram Nag, et al.
Journal of Medicinal Chemistry
|
October 18, 2022
Imaging Leucine-Rich Repeat Kinase 2 In Vivo with <sup>18</sup>F-Labeled Positron Emission Tomography Ligand
Zhen Chen, Jiahui Chen, Laigao Chen, et al.
Journal of Medicinal Chemistry
|
May 9, 2013
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand
Lei Zhang, Anabella Villalobos, Elizabeth M Beck, et al.
Nuclear Medicine and Biology
|
May 11, 2012
The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)
Marc B Skaddan, Lei Zhang, Douglas S Johnson, et al.
Molecular Imaging and Biology
|
June 18, 2021
Preclinical Evaluation of <sup>89</sup>Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy
Kevin P Maresca, Jianqing Chen, Divya Mathur, et al.
Clinical Pharmacology and Therapeutics
|
May 19, 2019
Positron Emission Tomography Imaging of [<sup>11</sup> C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A
Sarah Billington, Steven Shoner, Scott Lee, et al.
Journal of Medicinal Chemistry
|
January 23, 2018
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain
Lei Zhang, Laigao Chen, Jason K Dutra, et al.
Science Translational Medicine
|
August 17, 2022
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease
Ashwin V Venkataraman, Ayla Mansur, Gaia Rizzo, et al.
Page
of 3