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Cell Metabolism|January 2, 2009
Endoplasmic reticulum stress plays a central role in development of leptin resistanceLale Ozcan, Ayse Seda Ergin, Allen Lu, et al.Gastroenterology|September 2, 2017
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic SteatosisKyeongJin Kim, Dongryeol Ryu, Paola Dongiovanni, et al.Science (New York, N.Y.)|August 26, 2006
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesUmut Ozcan, Erkan Yilmaz, Lale Ozcan, et al.Nature|March 22, 2018
Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistanceDevram S Ghorpade, Lale Ozcan, Ze Zheng, et al.Cell Reports|May 31, 2016
Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin ResistanceLale Ozcan, Devram S Ghorpade, Ze Zheng, et al.The Journal of Clinical Investigation|July 14, 2020
Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesityZe Zheng, Keiko Nakamura, Shana Gershbaum, et al.Blood|December 4, 2018
An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1Ze Zheng, Lalitha Nayak, Wei Wang, et al.The Journal of Clinical Investigation|September 11, 2009
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathwaysJenelle M Timmins, Lale Ozcan, Tracie A Seimon, et al.Diabetes|June 13, 2015
Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin SensitivityLale Ozcan, Xiaoming Xu, Shi-Xian Deng, et al.The Journal of Clinical Investigation|October 4, 2017
CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosisAmanda C Doran, Lale Ozcan, Bishuang Cai, et al.Pageof 4