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Lalehan Oktay

Showing results (1-10 of 10) with videos related to

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Journal of Molecular Graphics & Modelling|April 13, 2024
Covalent docking-driven virtual screening of extensive small-molecule libraries against Bruton tyrosine kinase for the identification of highly selective and potent novel therapeutic candidatesEzgi Sambur, Lalehan Oktay, Serdar Durdağı
Turkish Journal of Biology = Turk Biyoloji Dergisi|July 25, 2024
A novel algorithm for the virtual screening of extensive small molecule libraries against ERCC1/XPF protein-protein interaction for the identification of resistance-bypassing potential anticancer moleculesSalma Ghazy, Lalehan Oktay, Serdar Durdaği
Chemmedchem|March 24, 2024
Developing Dynamic Structure-Based Pharmacophore and ML-Trained QSAR Models for the Discovery of Novel Resistance-Free RET Tyrosine Kinase Inhibitors Through Extensive MD Trajectories and NRI AnalysisEhsan Sayyah, Lalehan Oktay, Huseyin Tunc, et al.
ACS Omega|November 6, 2023
Utilizing Heteroatom Types and Numbers from Extensive Ligand Libraries to Develop Novel hERG Blocker QSAR Models Using Machine Learning-Based ClassifiersSafa Haddad, Lalehan Oktay, Ismail Erol, et al.
Turkish Journal of Biology = Turk Biyoloji Dergisi|November 22, 2021
Binary-QSAR guided virtual screening of FDA approved drugs and compounds in clinical investigation against SARS-CoV-2 main proteaseLalehan Oktay, Ece Erdemoğlu, İlayda Tolu, et al.
ACS Chemical Neuroscience|September 9, 2025
Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of RemyelinationMuge Didem Orhan, Lalehan Oktay, Ayşe Irem Cınar, et al.
Glia|August 3, 2023
Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degenerationBasma Sukkar, Lalehan Oktay, Ayse Sahaboglu, et al.
Oncogene|February 1, 2018
Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99Haydar Çelik, Marika Sciandra, Bess Flashner, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|October 22, 2021
The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studiesSerdar Durdagi, Timucin Avsar, Muge Didem Orhan, et al.
Structure (London, England : 1993)|August 17, 2021
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposingSerdar Durdagi, Çağdaş Dağ, Berna Dogan, et al.
Pageof 1

Showing results (1-10 of 10) with videos related to

Sort By:
Pageof 1
Journal of Molecular Graphics & Modelling|April 13, 2024
Covalent docking-driven virtual screening of extensive small-molecule libraries against Bruton tyrosine kinase for the identification of highly selective and potent novel therapeutic candidatesEzgi Sambur, Lalehan Oktay, Serdar Durdağı
Turkish Journal of Biology = Turk Biyoloji Dergisi|July 25, 2024
A novel algorithm for the virtual screening of extensive small molecule libraries against ERCC1/XPF protein-protein interaction for the identification of resistance-bypassing potential anticancer moleculesSalma Ghazy, Lalehan Oktay, Serdar Durdaği
Chemmedchem|March 24, 2024
Developing Dynamic Structure-Based Pharmacophore and ML-Trained QSAR Models for the Discovery of Novel Resistance-Free RET Tyrosine Kinase Inhibitors Through Extensive MD Trajectories and NRI AnalysisEhsan Sayyah, Lalehan Oktay, Huseyin Tunc, et al.
ACS Omega|November 6, 2023
Utilizing Heteroatom Types and Numbers from Extensive Ligand Libraries to Develop Novel hERG Blocker QSAR Models Using Machine Learning-Based ClassifiersSafa Haddad, Lalehan Oktay, Ismail Erol, et al.
Turkish Journal of Biology = Turk Biyoloji Dergisi|November 22, 2021
Binary-QSAR guided virtual screening of FDA approved drugs and compounds in clinical investigation against SARS-CoV-2 main proteaseLalehan Oktay, Ece Erdemoğlu, İlayda Tolu, et al.
ACS Chemical Neuroscience|September 9, 2025
Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of RemyelinationMuge Didem Orhan, Lalehan Oktay, Ayşe Irem Cınar, et al.
Glia|August 3, 2023
Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degenerationBasma Sukkar, Lalehan Oktay, Ayse Sahaboglu, et al.
Oncogene|February 1, 2018
Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99Haydar Çelik, Marika Sciandra, Bess Flashner, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|October 22, 2021
The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studiesSerdar Durdagi, Timucin Avsar, Muge Didem Orhan, et al.
Structure (London, England : 1993)|August 17, 2021
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposingSerdar Durdagi, Çağdaş Dağ, Berna Dogan, et al.
Pageof 1