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Cancer Research|July 3, 2004
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing AktLin Yang, Han C Dan, Mei Sun, et al.Cancer Research|May 20, 2004
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptorJiazhi Sun, Michelle A Blaskovich, Rishi K Jain, et al.Blood|February 25, 2005
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cellsKuichun Zhu, Elvira Gerbino, Darrin M Beaupre, et al.Antimicrobial Agents and Chemotherapy|November 11, 2009
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitroYao Cheng, Lun K Tsou, Jianfeng Cai, et al.Chemistry & Biology|February 28, 2009
Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferaseMichael A Hast, Steven Fletcher, Christopher G Cummings, et al.Organic & Biomolecular Chemistry|February 1, 2006
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferaseJunko Ohkanda, Corey L Strickland, Michelle A Blaskovich, et al.Journal of Medicinal Chemistry|May 26, 2009
Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas diseasePraveen Kumar Suryadevara, Srinivas Olepu, Jeffrey W Lockman, et al.The Journal of Clinical Investigation|August 5, 2003
In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virusBruno B Bordier, Junko Ohkanda, Ping Liu, et al.Bioorganic & Medicinal Chemistry|November 24, 2004
In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeabilityDora Carrico, Junko Ohkanda, Howard Kendrick, et al.Journal of Medicinal Chemistry|January 9, 2004
Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agentsJunko Ohkanda, Frederick S Buckner, Jeffrey W Lockman, et al.Pageof 22