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Biophysical Journal|December 7, 2020
Intrinsic Disorder in the T Cell Receptor Creates Cooperativity and Controls ZAP70 BindingLara Clemens, Omer Dushek, Jun Allard
Cytoskeleton (Hoboken, N.J.)|October 30, 2016
Computational simulation of formin-mediated actin polymerization predicts homologue-dependent mechanosensitivityDerek Bryant, Lara Clemens, Jun Allard
Expert Opinion on Drug Metabolism & Toxicology|May 5, 2025
A well-characterized mechanistic model for exploring known or hypothesized T cell mediated drug induced liver injury: current capabilities and challenges for future predictivityLara Clemens, Christina Battista, Zackary R Kenz, et al.
Pharmaceutics|March 27, 2025
Physiologically Based Pharmacokinetic Models for Infliximab, Ipilimumab, and Nivolumab Developed with GastroPlus to Predict Hepatic ConcentrationsCeleste Vallejo, Cameron Meaney, Lara Clemens, et al.
Biophysical Journal|March 30, 2021
Determination of the molecular reach of the protein tyrosine phosphatase SHP-1Lara Clemens, Mikhail Kutuzov, Kristina Viktoria Bayer, et al.
Biophysical Journal|September 24, 2019
The Influence of Molecular Reach and Diffusivity on the Efficacy of Membrane-Confined ReactionsYing Zhang, Lara Clemens, Jesse Goyette, et al.
Biophysical Journal|April 28, 2016
Multisite Phosphorylation Modulates the T Cell Receptor ζ-Chain Potency but not the Switchlike ResponseHimadri Mukhopadhyay, Ben de Wet, Lara Clemens, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 7, 2026
RENAsym, a Quantitative Systems Toxicology Platform Model, Designed to Predict Drug-Induced Kidney Injury Indicates Polymyxin B and Valproate Overdose Toxicity Potential While Simultaneously Demonstrating Acetaminophen and Valproate Safety at Therapeutic LevelsCeleste Vallejo, Pallavi Bhargava, Nader Hamzavi, et al.
International Journal of Molecular Sciences|June 10, 2023
The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver InjuryJames J Beaudoin, Lara Clemens, Mark T Miedel, et al.
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