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Angewandte Chemie (International Ed. in English)|February 10, 2021
Cell-Based Identification of New IDO1 Modulator ChemotypesElisabeth Hennes, Philipp Lampe, Lara Dötsch, et al.
Nature Communications|November 30, 2023
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand ChemotypeGang Xue, Jianing Xie, Matthias Hinterndorfer, et al.
Angewandte Chemie (International Ed. in English)|May 27, 2024
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2Sohan Patil, Gregor Cremosnik, Lara Dötsch, et al.
Angewandte Chemie (International Ed. in English)|August 12, 2022
Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor ChemotypeCaitlin Davies, Lara Dötsch, Maria Gessica Ciulla, et al.
Journal of Medicinal Chemistry|March 12, 2024
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway ModulatorLara Dötsch, Caitlin Davies, Elisabeth Hennes, et al.
Journal of Medicinal Chemistry|September 10, 2020
Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central PocketHacer Karatas, Mohammad Akbarzadeh, Hélène Adihou, et al.
Journal of Medicinal Chemistry|December 2, 2022
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast DifferentiationJana Flegel, Saad Shaaban, Zhi Jun Jia, et al.
Biorxiv : the Preprint Server for Biology|July 19, 2024
Identification of a Monovalent Pseudo-Natural Product Degrader Class Supercharging Degradation of IDO1 by its native E3 KLHDC3Elisabeth Hennes, Belén Lucas, Natalie S Scholes, et al.
Nature Chemistry|January 7, 2026
Monovalent pseudo-natural products supercharge degradation of IDO1 by its native E3 KLHDC3Elisabeth Hennes, Belén Lucas, Natalie S Scholes, et al.
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