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Journal of Medicinal Chemistry|April 18, 2009
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entryYijun Deng, Xilin Zhou, Sita Kugel Desmoulin, et al.Journal of Medicinal Chemistry|January 21, 2015
Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agentsYiqiang Wang, Shermaine Mitchell-Ryan, Sudhir Raghavan, et al.Pediatric Blood & Cancer|April 11, 2012
Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cellsChengzhi Xie, Holly Edwards, Salvatore B Lograsso, et al.Journal of Medicinal Chemistry|October 12, 2013
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisYiqiang Wang, Christina Cherian, Steven Orr, et al.Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|April 17, 2014
Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexedMugdha Patki, Shirish Gadgeel, Yanfang Huang, et al.Blood|April 4, 2002
High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemiaJeffrey W Taub, Mark A Konrad, Yubin Ge, et al.Biorxiv : the Preprint Server for Biology|May 16, 2025
Inhibition Of One-Carbon Metabolism In Ewing Sarcoma Results In Profound And Prolonged Growth Suppression Associated With Purine DepletionSara Zirpoli, Noah Copperman, Shrey Patel, et al.Cancer Research Communications|July 23, 2025
One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth SuppressionSara Zirpoli, Noah Copperman, Shrey Patel, et al.Blood|July 28, 2009
Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndromeDiane C Cabelof, Hiral V Patel, Qing Chen, et al.Plos One|July 23, 2013
Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic LeukemiaJohn Timothy Caldwell, Holly Edwards, Alan A Dombkowski, et al.Pageof 13