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Proceedings of the National Academy of Sciences of the United States of America|March 31, 2026
Spirocyclic β-lactone secondary metabolites modulate spliceosome functionKathryn E Penton, Sydney A Bates, Hannah L Thirman, et al.
The Journal of Experimental Medicine|September 2, 2022
Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responsesVidyanath Chaudhary, Marie Dominique Ah Kioon, Sung-Min Hwang, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 25, 2021
ATF6 is essential for human cone photoreceptor developmentHeike Kroeger, Julia M D Grandjean, Wei-Chieh Jerry Chiang, et al.
ACS Chemical Biology|June 20, 2025
Photoaffinity Ligand of Cystic Fibrosis Corrector VX-445 Identifies SCCPDH as an Off-TargetMinsoo Kim, Kwangho Kim, Jesun Lee, et al.
ACS Chemical Neuroscience|November 3, 2025
Improving Proteostasis of Trafficking-Deficient GABAA Receptor Variants by Activating IRE1Xu Fu, Ya-Juan Wang, KyungA Lee, et al.
Stem Cell Reports|November 29, 2013
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosisAmy Leung, Shirley K Nah, Whitney Reid, et al.
ACS Chemical Biology|April 15, 2025
Identification of a Selective Pharmacologic IRE1/XBP1s Activator with Enhanced Tissue ExposureJie Sun, Kyunga Lee, Sergei Kutseikin, et al.
Journal of the American Chemical Society|June 9, 2015
A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegansAleksandra Baranczak, Yu Liu, Stephen Connelly, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|January 12, 2025
Artificial enforcement of the unfolded protein response reduces disease features in multiple preclinical models of ALS/FTDVicente Valenzuela, Daniela Becerra, José I Astorga, et al.
Scientific Reports|July 7, 2026
Repairing Atp10D in C57Bl/6J mice restores protein expression but does not mitigate metabolic stress from high fat dietAlexander J Mansueto, Adriana C Norris, Eugenia M Yazlovitskaya, et al.
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