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Archives of Toxicology|August 11, 2018
The metabolic fate of fenclozic acid in chimeric mice with a humanized liverAnja Ekdahl, Lars Weidolf, Matthew Baginski, et al.Toxicology and Applied Pharmacology|October 1, 2008
Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergensLina Hagvall, Jens Malte Baron, Anna Börje, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 8, 2019
Metabolism of Strained Rings: Glutathione <i>S</i>-transferase-Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior BioactivationXue-Qing Li, Gunnar Grönberg, Eva-Henriette Bangur, et al.Journal of Medicinal Chemistry|July 17, 2019
Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic PathwaysFrancesca Toselli, Marlene Fredenwall, Peder Svensson, et al.Journal of Pharmaceutical Sciences|September 2, 2024
Early clinical drug product shelf-life setting using accelerated predictive stability and metabolite data for impurity qualification: A case studyJenny E Ottosson, Angela Ku, Magnus Fransson, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 11, 2017
Oxetane Substrates of Human Microsomal Epoxide HydrolaseFrancesca Toselli, Marlene Fredenwall, Peder Svensson, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|January 15, 2014
Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG miceKristin Samuelsson, Kathryn Pickup, Sunil Sarda, et al.Drug Discovery Today|April 16, 2021
Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugatesLars Weidolf, Anders Björkbom, Anders Dahlén, et al.Drug Metabolism Reviews|March 17, 2007
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applicationsLovisa Afzelius, Catrin Hasselgren Arnby, Anders Broo, et al.Chemico-Biological Interactions|November 16, 2010
Risk assessment and mitigation strategies for reactive metabolites in drug discovery and developmentRichard A Thompson, Emre M Isin, Yan Li, et al.Pageof 4